Sunday 18 September 2011

Weight Loss: In case of high-risk surgery allows it to live longer

This is the first study to investigate the survival associated with Bariatric Surgery or Obesity surgery on males of a certain age and at high risk of mortality. This surgery allows it to live longer? It is not so obvious, concluded the study published in the June 12 edition of JAMA.

After decades of rapid growth, the incidence of obesity peaked: In the United States, the prevalence of patients with a BMI over 35 increased by 39% between 2000 and 2005, the prevalence of obesity severe (BMI> 40) increased by 50% and the prevalence of superobésité (BMI> 50) increased by 75%. Obesity is difficult to treat and bariatric surgery has now been proven in weight loss for severe obese. The rates of obesity surgery in turn increases rapidly, however there are few studies on long-term survival after Bariatric Surgery.

To date, no studies have examined the long-term survival of patients at high risk of mortality associated with obesity, who underwent bariatric surgery. Here, a cohort of male patients at high risk rather old, which the authors compared in December 2008, with a control group that did not undergo bariatric surgery.

Mortality was followed for 850 veterans who had bariatric surgery from January 2000 to December 2006 (mean age 49.5 years, BMI: 47.4) compared to that of 41 244 controls (mean age 54.7 years, BMI average 42.0) on a median follow-up of 6.7 years. Several statistical models were used and compared.

· Among the patients who underwent bariatric surgery at 1, 2, and 6, the crude mortality rates were respectively 1.5%, 2.2% and 6.8% to 2.2% , 4.6% and 15.2% for control subjects without bariatric intervention.

• After modeling, bariatric surgery is associated with reduced mortality by 36% (HR 0.64, CI 95% 0.51 to 0.80). After adjusting for covariates, bariatric surgery is still associated with reduced mortality (HR 0.80, CI 95%, from 0.63 to 0.995).

· But in 1690 a group of matched patients, bariatric surgery is no longer associated with a significantly reduced mortality or unadjusted (HR 0.83, CI 95%, from 0.61 to 1.14) and not after adjustment over time (HR: 0.94, CI 95%, 0.64 to 1.39).

Conclusion: After adjustment with other possible risk factors, weight loss surgery is not associated with reduced mortality within 6 years of follow-up study.


Source:
JAMA Published online June 12, 2011. “Survival Among High-Risk Patients After Bariatric Surgery”

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